Daptomycin is an antibiotic used to treat complicated skin and skin structure infections that works by inhibiting bacterial cell wall synthesis.
Daptomycin CAS#103060-53-3
Daptomycin is an antibiotic used to treat complicated skin and skin structure infections that works by inhibiting bacterial cell wall synthesis.
Daptomycin is an important antibiotic used primarily to treat severe skin and skin structure infections, as well as certain types of bacterial endocarditis. It is produced by Streptomyces roseosporus and belongs to the cyclic peptide antibiotic class. It appears as a yellow or light yellow amorphous powder and is stored in sealed containers to ensure its stability and effectiveness.Daptomycin is particularly suitable for the treatment of Staphylococcus aureus (MRSA) that is resistant to other antibiotics, including methicillin-resistant Staphylococcus aureus (MRSA), intermediate vancomycin-resistant Staphylococcus aureus (VISA) and vancomycin-resistant Staphylococcus aureus (VRSA). Its mechanism of action is to disrupt the transport of amino acids by the cell membrane, hinder the biosynthesis of bacterial cell wall peptidoglycan, change the properties of the cytoplasmic membrane, and destroy the bacterial cell membrane to leak its contents, which binds to the bacterial membrane, interferes with the function of the bacterial cell membrane, causes the cell membrane to lose integrity#,thereby achieving the purpose of sterilization.Daptomycin is particularly effective against antibiotic-resistant bacteria and is a key drug for the treatment of complicated infections.
Daptomycin is widely used in clinical practice, especially in cases of infection that are poorly responsive to traditional antibiotics. It is often used to treat skin and skin structure infections, such as sepsis, cellulitis, and postoperative infections. The drug is administered by intravenous injection, and the treatment regimen is usually adjusted according to the type and severity of the infection to ensure maximum efficacy and safety.
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