D-Isoleucine is an important source of organic chirality and is increasingly used in the field of medicine.
D-ISOLEUCINE CAS#319-78-8
D-Isoleucine is an important source of organic chirality and is increasingly used in the field of medicine.
White flaky crystals or crystalline powder, odorless, slightly bitter in taste; soluble in water, slightly soluble in ethanol, insoluble in ether.
Used in biochemical research and as nutritional supplements in medicine.As an optically active organic acid, it plays an irreplaceable role in the asymmetric synthesis of certain chiral compounds ,mainly used in the preparation of chiral drugs, chiral additives, chiral auxiliaries, etc. It is also an important intermediate for the synthesis of antibacterial, anti-tumor, new broad-spectrum antibiotics, pharmaceutical supplements, etc.D-Isoleucine is an important organic chiral source, which is increasingly widely used in the field of medicine. As an optically active organic acid, it has an irreplaceable role in the asymmetric synthesis of certain chiral compounds, and is mainly used in the preparation of chiral drugs, chiral additives, chiral auxiliaries, etc. Meanwhile, it is also an important intermediate for the synthesis of antimicrobials, antitumors, and new types of broad-spectrum antibiotics, and pharmaceutical additives.
Bioactivity:D-Isoleucine ((R)-Isoleucine), an isoleucine stereoisomer, is a selective activator of the Asc-1 transporter protein, which enhances the long-term potentiation of hippocampal CA1-CA3 by releasing endogenous D-serine.
Main Functions and Applications:Biological and Physiological Functions:Amino Acid Metabolism: The metabolic process of D-isoleucine in the body is different from that of L-isoleucine. Due to its different stereoisomer structure, it is not directly involved in biosynthetic processes in most organisms, as only L-isoleucine is the form required for protein synthesis in the body.
Research Uses: D-Isoleucine is used to study the effects of stereoisomers of amino acids on living organisms, as well as in metabolic and enzymatic studies. Pharmaceutical and Medical Research:Drug Development: D-Isoleucine is sometimes used in drug development and research, particularly as an intermediate in chiral synthesis or as a test molecule for studying the response of drugs to stereoisomers.
Enzymatic Research: In enzymatic research, D-Isoleucine can be used to study the selectivity and catalytic mechanism of enzymes towards different stereoisomers.
Nutritional Supplements:Functional Studies: Although L-isoleucine is one of the essential amino acids and has a direct nutritional function in the human body, the study of D-isoleucine can help to understand the effect of the stereoisomerization of amino acids on physiological functions. However, D-isoleucine is not a common ingredient in nutritional supplements.
Industrial Applications:Chiral Synthesis: In organic chemistry and chiral synthesis, D-isoleucine can be used as a test compound or intermediate in the preparation of other chemical substances with specific stereochemical properties.
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