D-amino acids are an important class of chiral reagents and chiral intermediates.
D-Proline CAS#344-25-2
D-amino acids are an important class of chiral reagents and chiral intermediates.
Chemical Properties;D-Proline is white or light yellow solid powder at room temperature and pressure, with chiral center, so it is an optically active molecule, which can rotate plane-polarized light and has the value of spin, the carboxyl group and the amino group in D-Proline are the reaction centers that can be ionized, so it has acid-base properties. Under acidic conditions, it can be protonated to form the corresponding positively charged ions; under alkaline conditions, it can be deprotonated to form the negatively charged ions of D-proline. The carboxyl and amino groups in the structure of the compound can undergo condensation reactions to form peptide bonds. Applications: D-Proline can be used as organic synthesis and medicinal chemistry intermediates, mostly used in drug molecules and biologically active molecules modification, for example, D-Proline can be used for the synthesis of &B-carotene, in the organic synthesis conversion, D-Proline can be esterified under acidic conditions to produce the corresponding amino ester derivatives.
Use I is used in the synthesis of pharmaceuticals.
Use 2 is used in the asymmetric self-condensation reaction of &B-ionylideneacetaldehyde, retinal and related compounds.
Applications: Medical Research:Protein Research: D-Proline is used to study the three-dimensional structure and folding mechanism of proteins, especially in some specific protein folding patterns.
Drug Development: In drug design, D-Proline can be used as a component of drug molecules to modify the biological activity or stability of the molecule.
Synthetic Chemistry:Chiral Catalyst: D-Proline can be used as a chiral catalyst to facilitate the synthesis of certain chiral compounds. This is very useful in organic synthesis, especially in the preparation of chiral drugs and functional compounds.
Chemical Synthesis: As a reaction reagent, D-Proline can be used to synthesize novel chemicals, including complex organic molecules and materials.
Materials Science: Development of New Materials: Due to its special structure, D-Proline may be used to develop novel materials, especially in applications requiring specific molecular arrangements or functions. Food and Nutraceuticals: Research and Applications: Although uncommon, D-Proline may be used as a research ingredient in foods and nutraceuticals to explore potential effects on food quality or health.
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