L-Leucine is one of the nine essential amino acids, meaning the body cannot produce it on its own and it must be obtained through diet.
L-LeucineCAS NO.61-90-5
L-Leucine is one of the nine essential amino acids, meaning the body cannot produce it on its own and it must be obtained through diet.
L-Leucine is a white crystalline powder or granule. It is one of the essential amino acids for the human body. It cannot be synthesized by itself and must be ingested through diet. As part of the branched chain amino acids (BCAA), it plays a key role in protein synthesis and muscle repair, especially helping to promote muscle growth and recovery after exercise. L-leucine can also help regulate blood sugar levels, enhance energy metabolism, and slow down muscle breakdown, which is particularly beneficial to athletes and fitness enthusiasts. In addition, leucine also has certain effects in improving immunity in the body and supporting liver function, and is often used as a dietary supplement.
Functions and applications:
1 Protein Synthesis: L-Leucine is a key regulator of protein synthesis, particularly in muscle tissue. It activates a pathway known as the mammalian target of rapamycin (mTOR) pathway, which stimulates muscle protein synthesis. This makes leucine especially important for athletes, bodybuilders, and individuals looking to optimize muscle growth and recovery.
2 Muscle Growth and Repair: L-Leucine is commonly used in sports nutrition supplements, often in combination with other branched-chain amino acids (BCAAs), to support muscle growth and repair. It helps maintain muscle mass during periods of exercise, dieting, or injury by promoting protein synthesis and inhibiting protein breakdown.
3 Energy Production: Beyond its role in protein synthesis, L-leucine can also be oxidized within muscle cells to provide energy during prolonged exercise or periods of fasting. It serves as a substrate for the production of acetyl-CoA, a key molecule in the energy-producing pathways of the body.
4 Regulation of Blood Sugar Levels: L-Leucine has been shown to play a role in the regulation of blood sugar levels and insulin secretion. It can enhance insulin sensitivity, helping to improve glucose uptake by muscle cells and reduce the risk of insulin resistance and type 2 diabetes.
5 Appetite Regulation: Some research suggests that L-leucine may play a role in appetite regulation and satiety. It may help reduce food intake by promoting the release of hormones that signal fullness, potentially aiding in weight management efforts.
6 Wound Healing: L-Leucine is involved in the synthesis of collagen and other structural proteins necessary for wound healing and tissue repair. It contributes to the formation of new tissue and the restoration of skin integrity following injury or surgery.
7 Dietary Sources: Foods rich in L-leucine include meat (especially beef, chicken, and pork), fish, dairy products (such as cheese, milk, and yogurt), eggs, legumes (like beans and lentils), nuts, seeds, and certain grains (such as wheat and rice).
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